Wilms’ Tumor: Experience of Regional Children’s Hospital in Serbia

Malignancy in children presents the major cause of death due to disease between the ages of 1 and 15 year. Tumors differ from tumors in adult age in their nature, localization and prognosis. The basic challenge of pediatric oncology is adjustment of therapy to the biological nature and stage of malignant process, while not interfering with growth and development of the child. The most frequent tumors in children are acute lymphoblast leukemia, tumors of the central nervous system and sarcomas. Tumors of the kidney present 10% of tumors in the first 5 years of life and 5% of tumors between the 5-9 years of age. Pediatric oncology management in Europe is according to the SIOP protocols. SIOP (Société Internationale d’Oncologie Pédiatrique) is international association of pediatric oncologist which was founded in Geneva, Switzerland in 1960 [1,2].